Complex and molecular trait variants paper on BioRxiv!

We’re excited to share this collaboration with the Tewhey Lab, along with the Sabeti, Finucane, and Lander labs and massive efforts by Layla Siraj and Jacob Ulirsch. In it, we test nearly all fine-mapped trait associated variants in the UK Biobank and GTEx. Thats a whopping 221,412 variants! You can read the pre-print or read through Layla’s tweetorial below!

Could not be more delighted to present our work investigating how over 220,000 complex and molecular trait-associated genetic variants affect transcriptional regulation using massively parallel reporter assays!https://t.co/1eoN4OxAvd
See below for a 🧵. 1/n

— Layla Siraj, Ph.D. (@LaylaSiraj) May 6, 2024